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Drug ReportsEstrogens esterified
Estrogens esterified
Amnestrogen, Duavee, Estratab, Evex, Femogen, Menest, Menrium, Milprem, Pmb, Premarin, Premphase, Prempro (estrogens, esterified) is an unknown pharmaceutical. Estrogens, esterified was first approved as Menrium 5-2 on 1982-01-01.
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Events Timeline
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name
Status
Last Update
covaryxunapproved drug other2020-01-25
covaryx covaryxunapproved drug other2013-02-26
duaveeNew Drug Application2025-01-13
eemtunapproved drug other2020-01-22
eemt eemtunapproved drug other2013-03-01
esterified estrogens and methyltestosteroneunapproved drug other2025-02-10
esterified estrogens and methyltestosterone full strength esterified estrogens and methyltestosterone half strengthunapproved drug other2025-03-10
esterified estrogens and methytestesteroneunapproved drug other2022-11-25
estratest f.s.unapproved drug other2024-09-06
estratest f.s. estratest h.s.unapproved drug other2024-06-15
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
Patent
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Flag
FDA Information
Bazedoxifene Acetate / Estrogens, Conjugated, Duavee, Wyeth Pharms
76830512027-03-10DS, DPU-594, U-904
64795352024-05-06DPU-594, U-904
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
1440 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———5—1——6
AtrophyD001284————2——2
ContraceptionD003267————1——1
DyspareuniaD004414—N94.1——1——1
VaginitisD014627EFO_0005757N76——1——1
Atrophic vaginitisD059268EFO_1001271———1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HemostasisD006487———2———2
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Therapeutic equivalencyD013810——1————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameEstrogens esterified
INN—
Description
17beta-estradiol is the 17beta-isomer of estradiol. It has a role as an estrogen, a human metabolite, an EC 1.2.3.1 (aldehyde oxidase) inhibitor, a Daphnia magna metabolite, a mouse metabolite and a geroprotector. It is a 17beta-hydroxy steroid and an estradiol.
Classification
Unknown
Drug classestrogens; steroids (androgens, anabolics)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL1201468
ChEBI ID—
PubChem CID—
DrugBankDB09381
UNII ID—
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Premarin – Pfizer
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Estimated US medical usage
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 52,546 documents
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Safety
Black-box Warning
Black-box warning for: Covaryx, Covaryx covaryx, Duavee, Eemt, Eemt eemt, Esterified estrogens and methyltestosterone, Esterified estrogens and methyltestosterone full strength esterified estrogens and methyltestosterone half strength, Esterified estrogens and methytestesterone, Estratest f.s., Estratest f.s. estratest h.s., Estratest fs estratest hs, Menest, Premarin, Premphase, Premphase prempro, Prempro
Adverse Events
Top Adverse Reactions
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104,985 adverse events reported
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